Acute phase protein levels in dogs with mast cell tumours and sarcomas
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چکیده
منابع مشابه
Acute phase protein levels in dogs with mast cell tumours and sarcomas.
The acute phase proteins (APP) form part of a non-specific host response to inflammation. They may be induced by a range of different causes, including infection, inflammation, cancer and trauma. As they form part of the earliest response to such insults, they have potential for early identification of disease. In people, APP levels have been shown to correlate both with the extent of disease a...
متن کاملCutaneous mast cell tumours in dogs.
Canine mast cell tumors (MCT) vary greatly, and no prediction can be made for their behavior on clinical appearance alone. Important prognostic information can be gained from histologic grading and assessment of surgical margins. Surgical excision is indicated if the tumour is solitary and is the treatment of choice for grade 1 and 2 MCT. Excision should include a minimum 2cm margin around the ...
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OBJECTIVES To evaluate the response of measurable canine mast cell tumours unsuitable for other treatment modalities to a chemotherapy protocol comprising chlorambucil and prednisolone. METHODS Dogs bearing measurable mast cell tumours, unsuitable for treatment by surgery or radiotherapy, were treated with orally administered prednisolone and chlorambucil, and their responses assessed. RESU...
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Optimal chemotherapy protocols for high-risk mast cell tumours (MCTs) are unknown. The purpose of this study was to determine the tolerability and toxicity profile of a rapidly escalating vinblastine and prednisolone protocol (VPP) in which 3.00 mg/m2 was administered once 7 days apart: at day 14 and at day 21. Dogs with chemotherapy-naïve MCTs presenting to the Oncology Service of a single ins...
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The concentrations of C-reactive protein (CRP), serum amyloid A, haptoglobin (Hp) and α(1)-acid glycoprotein were measured in dogs with clinical signs of nasal disease and compared with those of healthy dogs in order to determine the expression of these proteins in cases of canine nasal disease. A significant difference (P<0.001) between the symptomatic group and the control group was found for...
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ژورنال
عنوان ژورنال: Veterinary Record
سال: 2012
ISSN: 0042-4900
DOI: 10.1136/vr.100401